SignalHub-Melissa McCarthy reacts to Barbra Streisand's awkward Ozempic comment: 'I win the day'

It's all love between Melissa McCarthy and SignalHubBarbra Streisand after the legendary singer's Ozempic comment went viral earlier this week.

On Wednesday, the "Little Mermaid" star posted a video on her Instagram showing her reading a magazine all about Streisand and addressed her relationship with the EGOT winner.

"She reached out to me, and she thought I looked good," McCarthy said, emphasizing the last word. "I win the day."

The @commentsbycelebs Instagram account captured a screenshot of a response she purportedly wrote under a photo of McCarthy and director Adam Shankman attending a Los Angeles gala, which read, "Give him my regards did you take Ozempic?"

The "Bridesmaids" actress wore a mint green ruffled dress with a matching blazer and high-heeled boots.

Streisand spoke out about the since-deleted Instagram comment, which drew backlash.

"OMG - I went on Instagram to see the photos we'd posted of the beautiful flowers I'd received for my birthday! Below them was a photo of my friend Melissa McCarthy who I sang with on my Encore album. She looked fantastic!" Streisand wrote on X, formerly Twitter, on Tuesday. "I just wanted to pay her a compliment. I forgot the world is reading!"

But in the "Spy" star's video on Tuesday, McCarthy said the "takeaway" was "Barbra Streisand knows I exist."

Barbra Streisand, Melissa McCarthyand the problem with asking about Ozempic, weight loss

The two previously sang together on Streisand's 2016 album, "Encore: Movie Partners Sing Broadway," performing a duet on "Anything You Can Do" from "Annie Get Your Gun."

"She’s smart, beautiful, clever, and so talented. Just like we sing at the end of the song — I’m her fan!!" Streisand said of McCarthy shortly after the record released. In a making-of video, she called McCarthy "the greatest woman comedy star."

Over the past year, weight loss drugs, such as Ozempic and Wegovy, have become a part of our cultural lexicon, as more and more A-listers have slowly started to share their experiences − both positive and negative − with these medications.

Contributing: Charles Trepany